Associations of Hormone-Related Factors With Breast Cancer Risk According to Hormone Receptor Status Among White and African American Women

Associations of Hormone-Related Factors With Breast Cancer Risk According to Hormone Receptor Status Among White and African American Women

Micro-Abstract This study examined racial differences in the distribution of breast cancer by receptor status and evaluated the associations of menstrual and reproductive factors with risk of breast cancer by race and subtypes defined by estrogen receptor status in a case-control study including 186...

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Veröffentlicht in:Clinical breast cancer 2014-12, Vol.14 (6), p.417-425
Hauptverfasser: Cui, Yong, Deming-Halverson, Sandra L, Shrubsole, Martha J, Beeghly-Fadiel, Alicia, Fair, Alecia M, Sanderson, Maureen, Shu, Xiao-Ou, Kelley, Mark C, Zheng, Wei
Format: Artikel
Sprache:eng
Schlagworte:
Adult
African Americans - statistics & numerical data
Aged
Biomarkers, Tumor - metabolism
Breast Neoplasms - etiology
Breast Neoplasms - metabolism
Breast Neoplasms - pathology
Case-Control Studies
Epidemiology
Estrogen receptor
European Continental Ancestry Group - statistics & numerical data
Female
Follow-Up Studies
Hematology, Oncology and Palliative Medicine
Hormone receptor status
Humans
Menopause
Middle Aged
Neoplasm Grading
Neoplasm Staging
Obstetrics and Gynecology
Prognosis
Race
Receptor, ErbB-2 - metabolism
Receptors, Estrogen - metabolism
Receptors, Progesterone - metabolism
Risk Factors
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Beschreibung
Zusammenfassung:Micro-Abstract This study examined racial differences in the distribution of breast cancer by receptor status and evaluated the associations of menstrual and reproductive factors with risk of breast cancer by race and subtypes defined by estrogen receptor status in a case-control study including 1866 breast cancer cases and 2306 controls. The study suggests that certain hormone-related factors are differentially associated with breast cancer subtypes, and these associations also differ by race.
ISSN:1526-8209
1938-0666
DOI:10.1016/j.clbc.2014.04.003