Helicobacter pylori infection in hemodialysis patients： Susceptibility to amoxicillin and clarithromycin

AIM: To evaluate susceptibility of Helicobacter pylori to amoxicillin and clarithromycin in end-stage renal disease(ESRD) patients and non-uremic controls.METHODS: The subjects with dyspeptic complaints were 33 ESRD patients and 46 age- and sex-matched nonuremic controls who exhibited Hpylorion antral biopsy specimens. The two groups were age and sex matched.The Hpyloristrains' pattern of susceptibility to amoxicillin and clarithromycin was investigated with the agar dilution technique.RESULTS: None of the Hpyloristrains from either group showed resistance to amoxicillin with the agar dilution method. Twelve (36.4%) of the ESRD group strains and7 (15.2%) of the control group strains showed resistance to clarithromycin, and this difference was statistically significant (P