Toward Intelligent Synthetic Neural Circuits: Directing and Accelerating Neuron Cell Growth by Self-Rolled-Up Silicon Nitride Microtube Array
In neural interface platforms, cultures are often carried out on a flat, open, rigid, and opaque substrate, posing challenges to reflecting the native microenvironment of the brain and precise engagement with neurons. Here we present a neuron cell culturing platform that consists of arrays of ordere...
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| Veröffentlicht in: | ACS nano 2014-11, Vol.8 (11), p.11108-11117 |
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| creator | Froeter, Paul Huang, Yu Cangellaris, Olivia V Huang, Wen Dent, Erik W Gillette, Martha U Williams, Justin C Li, Xiuling |
| description | In neural interface platforms, cultures are often carried out on a flat, open, rigid, and opaque substrate, posing challenges to reflecting the native microenvironment of the brain and precise engagement with neurons. Here we present a neuron cell culturing platform that consists of arrays of ordered microtubes (2.7–4.4 μm in diameter), formed by strain-induced self-rolled-up nanomembrane (s-RUM) technology using ultrathin ( |
| doi_str_mv | 10.1021/nn504876y |
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| subjects | Arrays Cell Division Construction Culture Fluorescence Microscopy, Electron, Scanning Nanostructure Neural Networks (Computer) Neurons Neurons - cytology Platforms Silicon Compounds Silicon nitride Three dimensional |
| title | Toward Intelligent Synthetic Neural Circuits: Directing and Accelerating Neuron Cell Growth by Self-Rolled-Up Silicon Nitride Microtube Array |
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