Canadian Cardiovascular Harmonized National Guidelines Endeavour (C-CHANGE): 2014 update

Competing interests: [Sheldon W. Tobe MD] has received research funding from Eli Lilly and Company, AstraZeneca, Abb Vie and Bayer. [James A. Stone MD PhD] has received funding from Amgen, Forest Laboratories, Merck and Sanofi. [Todd Anderson MD] declares research study involvement with Merck and Amgen. [Onil Bhattacharyya MD PhD] has received funding from GlaxoSmith- Kline, Merck, Merck Serono and Novartis. Alice Cheng declares personal fees from AstraZeneca, Boehringer Ingel- heim, Eli Lilly and Company, Janssen, Merck, Novo Nord- isk, Sanofi, Servier, Valeant Pharmaceuticals International, Abbott and Takeda Pharmaceutical Company. Cord Gubitz has received funds from Pfizer-Bristol-Myers Squibb, Bayer and Boehringer Ingelheim, and is a member of the steering committee for the Heart and Stroke Foundation of Canada Stroke Best Practices. David Lau declares receiving funds from AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Eli Lilly and Company, Janssen, Merck, Novo Nord- isk, Roche, Sanofi and Valeant Pharmaceuticals Interna- tional. Lawrence Leiter declares grants or personal fees from AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Eli Lilly and Company, GlaxoSmithKline, Janssen, Merck, Novartis, Novo Nordisk, Roche, Sanofi, Servier, Takeda Pharmaceutical Company and Amgen. Raj Padwal has received funds from Forest Laboratories, Medtronic, Novo Nordisk, CVRx, Valencia, Abbott, Servier and Merck. [Peter Selby MD, Mark Tremblay PhD] has received funds from Pfizer and AbbVie. No com- peting interests were declared by [Kimberly M. Walker MPH], Onil Bhattacharyya, [Jean Gr]égoire, Gord Gubitz, Mary L'Abbé, Paul Oh, [Luc Poirier MSc], Mark Tremblay, [Richard A. Ward MD] and [Diane Hua MPH]. Affiliations: Division of Nephrology (Tobe), Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ont.; Libin Cardiovascular Institute of Alberta (Stone), Uni- versity of Calgary, Cardiac Wellness Institute of Calgary, Calgary, Alta.; University Health Network, Toronto General Hospital (Walker), Toronto, Ont.; Libin Cardiovascular Insti- tute of Alberta (Anderson), University of Calgary Calgary Alta.; Women's College Hospital (Bhattacharrya), University of Toronto, Toronto, Ont.; Division of Endocrinology and Metabolism (Cheng), St. Michael's Hospital, University of Toronto, Toronto, Ont.; Institut de cardiologie de Montréal (Grégoire), Université de Montréal, Montréal, Que.; Division of Neurology (Gubitz), Dalhousie University, Halifax, NS