RM-03ACQUISITION OF STEM-CELL PHENOTYPE THROUGH EPITHELIAL MESENCHYMAL TRANSITION IN GLIOBLASTOMA

RM-03ACQUISITION OF STEM-CELL PHENOTYPE THROUGH EPITHELIAL MESENCHYMAL TRANSITION IN GLIOBLASTOMA

The stem cell phenotype including high motility of the cells and resistance to apoptosis usually contributes to the aggressiveness of glioblastoma (GB). To examine the molecular mechanisms of treatment resistance, we comprehensively compared protein expressions between a group of patients with good...

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Veröffentlicht in:Neuro-oncology (Charlottesville, Va.) Va.), 2014-11, Vol.16 (Suppl 5), p.v186-v186
Hauptverfasser: Iwadate, Yasuo, Suganami, Akiko, Tamura, Yutaka, Matsutani, Tomoo, Hirono, Seiichiro, Shinozaki, Natsuki, Ikegami, Shiro, Saeki, Naokatsu
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Sprache:eng
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Zusammenfassung:The stem cell phenotype including high motility of the cells and resistance to apoptosis usually contributes to the aggressiveness of glioblastoma (GB). To examine the molecular mechanisms of treatment resistance, we comprehensively compared protein expressions between a group of patients with good prognosis (survival >4 years) and a group with poor prognosis (survival
ISSN:1522-8517
1523-5866
DOI:10.1093/neuonc/nou273.3