18F-Alfatide II and 18F-FDG Dual Tracer Dynamic PET for Parametric, Early Prediction of Tumor Response to Therapy

A single dynamic PET acquisition using multiple tracers administered closely in time could provide valuable complementary information about a tumor’s status under quasi-constant conditions. This study aims to investigate the utility of dual-tracer dynamic PET imaging with 18 F-Alfatide II ( 18 F-AlF...

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Veröffentlicht in:The Journal of nuclear medicine (1978) 2013-11, Vol.55 (1), p.154-160
Hauptverfasser: Guo, Jinxia, Guo, Ning, Lang, Lixin, Kiesewetter, Dale O., Xie, Qingguo, Li, Quanzheng, Eden, Henry S., Niu, Gang, Chen, Xiaoyuan
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Sprache:eng
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Zusammenfassung:A single dynamic PET acquisition using multiple tracers administered closely in time could provide valuable complementary information about a tumor’s status under quasi-constant conditions. This study aims to investigate the utility of dual-tracer dynamic PET imaging with 18 F-Alfatide II ( 18 F-AlF-NOTA-E[PEG 4 -c(RGDfk)] 2 ) and 18 F-FDG for parametric monitoring of tumor responses to therapy.
ISSN:0161-5505
1535-5667
DOI:10.2967/jnumed.113.122069