Stress-enhanced translation of γ-globin mRNA
In this issue of Blood , Hahn and Lowrey demonstrate enhanced translation of γ-globin messenger RNA (mRNA) upon activation of eukaryotic initiation factor 2αP (eIF2αP) stress signaling. This finding underscores translational control as a novel mechanism in regulating fetal hemoglobin production (HbF...
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| Veröffentlicht in: | Blood 2014-10, Vol.124 (17), p.2622-2623 |
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| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | In this issue of
Blood
, Hahn and Lowrey demonstrate enhanced translation of γ-globin messenger RNA (mRNA) upon activation of eukaryotic initiation factor 2αP (eIF2αP) stress signaling. This finding underscores translational control as a novel mechanism in regulating fetal hemoglobin production (HbF).
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| ISSN: | 0006-4971 1528-0020 |
| DOI: | 10.1182/blood-2014-09-599290 |