A biochemical study on ameliorative effect of green tea (Camellia sinensis) extract against contrast media induced acute kidney injury

Reactive oxygen species have been shown to be mediators of kidney injury and green tea polyphenols are potent-free radical scavengers. In this study we sought to examine whether green tea was able to protect renal toxicity induced by contrast media or not. In this experimental study 40 rats were randomly divided into four groups including: 1) control group 2) contrast media group 3) contrast media plus green tea 4) Green tea pretreatment and contrast media group. Blood urea Nitrogen (BUN) and serum creatinine were assessed for severity of kidney injury. Serum creatinine level was higher in group II than in other groups (p