Sequence types 235, 111, and 132 predominate among multidrug-resistant pseudomonas aeruginosa clinical isolates in Croatia

A population analysis of 103 multidrug-resistant Pseudomonas aeruginosa isolates from Croatian hospitals was performed. Twelve sequence types (STs) were identified, with a predominance of international clones ST235 (serotype O11 [41%]), ST111 (serotype O12 [15%]), and ST132 (serotype O6 [11%]). Over...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2014-10, Vol.58 (10), p.6277-6283
Hauptverfasser:	Guzvinec, Marija, Izdebski, Radosław, Butic, Iva, Jelic, Marko, Abram, Maja, Koscak, Iva, Baraniak, Anna, Hryniewicz, Waleria, Gniadkowski, Marek, Tambic Andrasevic, Arjana
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents Anti-Bacterial Agents - pharmacology beta-Lactamases - genetics Cephalosporinase - genetics Croatia Drug Resistance, Multiple, Bacterial - genetics Epidemiology and Surveillance Pseudomonas aeruginosa Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - enzymology Pseudomonas aeruginosa - genetics
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Zusammenfassung:	A population analysis of 103 multidrug-resistant Pseudomonas aeruginosa isolates from Croatian hospitals was performed. Twelve sequence types (STs) were identified, with a predominance of international clones ST235 (serotype O11 [41%]), ST111 (serotype O12 [15%]), and ST132 (serotype O6 [11%]). Overexpression of the natural AmpC cephalosporinase was common (42%), but only a few ST235 or ST111 isolates produced VIM-1 or VIM-2 metallo-β-lactamases or PER-1 or GES-7 extended-spectrum β-lactamases.
ISSN:	0066-4804 1098-6596
DOI:	10.1128/aac.03116-14