Shigella Isolates From the Global Enteric Multicenter Study Inform Vaccine Development

Background. Shigella, a major diarrheal disease pathogen worldwide, is the target of vaccine development. The Global Enteric Multicenter Study (GEMS) investigated burden and etiology of moderate-to-severe diarrheal disease in children aged

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Veröffentlicht in:	Clinical infectious diseases 2014-10, Vol.59 (7), p.933-941
Hauptverfasser:	Livio, Sofie, Strockbine, Nancy A., Panchalingam, Sandra, Tennant, Sharon M., Barry, Eileen M., Marohn, Mark E., Antonio, Martin, Hossain, Anowar, Mandomando, Inacio, Ochieng, John B., Oundo, Joseph O., Qureshi, Shahida, Ramamurthy, Thandavarayan, Tamboura, Boubou, Adegbola, Richard A., Hossain, Mohammed Jahangir, Saha, Debasish, Sen, Sunil, Faruque, Abu Syed Golam, Alonso, Pedro L., Breiman, Robert F., Zaidi, Anita K. M., Sur, Dipika, Sow, Samba O., Berkeley, Lynette Y., O'Reilly, Ciara E., Mintz, Eric D., Biswas, Kousick, Cohen, Dani, Farag, Tamer H., Nasrin, Dilruba, Wu, Yukun, Blackwelder, William C., Kotloff, Karen L., Nataro, James P., Levine, Myron M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Africa - epidemiology Agglutination Tests and Commentaries Antigens ARTICLES AND COMMENTARIES Asia - epidemiology Bacillary dysentery Bacterial Typing Techniques Case-Control Studies Child, Preschool Children & youth Diarrhea Disease control Drug Discovery - methods Dysentery Dysentery, Bacillary - epidemiology Dysentery, Bacillary - microbiology Epidemiology Female Humans Infant Infant, Newborn Male Multicenter studies O antigens Serotyping Shigella Shigella - classification Shigella - isolation & purification Shigella flexneri Shigella vaccine Shigella Vaccines - immunology Shigella Vaccines - isolation & purification Vaccines
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Beschreibung
Zusammenfassung:	Background. Shigella, a major diarrheal disease pathogen worldwide, is the target of vaccine development. The Global Enteric Multicenter Study (GEMS) investigated burden and etiology of moderate-to-severe diarrheal disease in children aged
ISSN:	1058-4838 1537-6591
DOI:	10.1093/cid/ciu468