Correlates and reference limits of plasma gamma-glutamyltransferase fractions from the Framingham Heart Study

Correlates and reference limits of plasma gamma-glutamyltransferase fractions from the Framingham Heart Study

We assessed GGT fractions correlates and their reference values in the Offspring Cohort of the Framingham Heart Study. Correlates of GGT fractions were assessed by multivariable regression analysis in 3203 individuals [47% men, mean age (SD): 59 (10) years]. GGT fractions reference values were estab...

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Veröffentlicht in:Clinica chimica acta 2013-02, Vol.417, p.19-25
Hauptverfasser: Franzini, Maria, Fornaciari, Irene, Rong, Jian, Larson, Martin G., Passino, Claudio, Emdin, Michele, Paolicchi, Aldo, Vasan, Ramachandran S.
Format: Artikel
Sprache:eng
Schlagworte:
Blood Chemical Analysis - standards
Cohort Studies
Female
gamma-Glutamyltransferase - blood
Gamma-glutamyltransferase activity
Gamma-glutamyltransferase fractions
Gel-filtration chromatography
Health Surveys
Heart
Humans
Linear Models
Male
Markers
Middle Aged
Reference Values
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Zusammenfassung:We assessed GGT fractions correlates and their reference values in the Offspring Cohort of the Framingham Heart Study. Correlates of GGT fractions were assessed by multivariable regression analysis in 3203 individuals [47% men, mean age (SD): 59 (10) years]. GGT fractions reference values were established by empirical quantile analysis in a reference group of 432 healthy subjects [45% men, 57 (10) years]. Fractional GGT levels were higher in men than in women (P
ISSN:0009-8981
1873-3492
DOI:10.1016/j.cca.2012.12.002