Variability of magnetoencephalographic sensor sensitivity measures as a function of age, brain volume and cortical area

Highlights • MEG sensor sensitivity and focality vary appreciably with age, head size and brain size. • Findings provide a solid biophysical and methodological basis for the interpretation of MEG pediatric studies. • Our quantitative assessments of pediatric MEG lead fields should be taken into acco...

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Veröffentlicht in:	Clinical neurophysiology 2014-10, Vol.125 (10), p.1973-1984
Hauptverfasser:	Irimia, Andrei, Erhart, Matthew J, Brown, Timothy T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Factors Boundary element method Cerebral Cortex - anatomy & histology Cerebral Cortex - physiology Child Child, Preschool Feasibility Studies Female Humans Infant Lead field Magnetoencephalography Magnetoencephalography - methods Magnetoencephalography - standards Male Modeling Models, Neurological Neurology Pediatrics Sensitivity and Specificity Young Adult
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Beschreibung
Zusammenfassung:	Highlights • MEG sensor sensitivity and focality vary appreciably with age, head size and brain size. • Findings provide a solid biophysical and methodological basis for the interpretation of MEG pediatric studies. • Our quantitative assessments of pediatric MEG lead fields should be taken into account when designing and interpreting pediatric MEG experiments.
ISSN:	1388-2457 1872-8952
DOI:	10.1016/j.clinph.2014.01.027