Low-calcium serum-free defined medium selects for growth of normal prostatic epithelial stem cells

Stage-specific differentiation markers were used to evaluate the cellular composition and the origin of nonimmortalized (PrEC) and immortalized (PZ-HPV7, CA-HPV10, RWPE-1, and 957E/hTERT) human prostate cell lines. These studies documented that immortalized and nonimmortalized prostate epithelial ce...

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Veröffentlicht in:Cancer research (Chicago, Ill.) Ill.), 2006-09, Vol.66 (17), p.8598-8607
Hauptverfasser: LITVINOV, Ivan V, VANDER GRIEND, Donald J, YI XU, ANTONY, Lizamma, DALRYMPLE, Susan L, ISAACS, John T
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Sprache:eng
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Zusammenfassung:Stage-specific differentiation markers were used to evaluate the cellular composition and the origin of nonimmortalized (PrEC) and immortalized (PZ-HPV7, CA-HPV10, RWPE-1, and 957E/hTERT) human prostate cell lines. These studies documented that immortalized and nonimmortalized prostate epithelial cells established and maintained in low (i.e.,
ISSN:0008-5472
1538-7445
DOI:10.1158/0008-5472.CAN-06-1228