Reduced Chrna7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABAA receptor subunits

Highlights • Reduced Chrna7 expression is associated with increased hippocampal parvalbumin. • Reduced Chrna7 expression is associated with increased hippocampal GAD67. • Reduced Chrna7 expression alters hippocampal GABAA receptor subunit levels.

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Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience 2014-07, Vol.273, p.52-64
Hauptverfasser:	Bates, R.C, Stith, B.J, Stevens, K.E, Adams, C.E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and adolescent clinical studies Biological and medical sciences Chrna7 Fundamental and applied biological sciences. Psychology GABAA receptors glutamate decarboxylase 67 (GAD67) Medical sciences Neurology parvalbumin Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Schizophrenia Vertebrates: nervous system and sense organs λ-aminobutyric acid (GABA)
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Beschreibung
Zusammenfassung:	Highlights • Reduced Chrna7 expression is associated with increased hippocampal parvalbumin. • Reduced Chrna7 expression is associated with increased hippocampal GAD67. • Reduced Chrna7 expression alters hippocampal GABAA receptor subunit levels.
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2014.05.004