Kolaviron, isolated from Garcinia kola, inhibits acetylcholinesterase activities in the hippocampus and striatum of wistar rats

Kolaviron, isolated from seeds of Garcinia kola, have been shown to possess wide pharmacological properties. The present study examined the effect of kolaviron on acetylcholinesterase activities in the hippocampus and striatum of adult Wistar rats. In this study, histological and histochemical metho...

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Veröffentlicht in:Annals of Neurosciences 2013-04, Vol.20 (2), p.42-46
Hauptverfasser: Ijomone, Omamuyovwi M, Obi, Augustine U
Format: Artikel
Sprache:eng
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Zusammenfassung:Kolaviron, isolated from seeds of Garcinia kola, have been shown to possess wide pharmacological properties. The present study examined the effect of kolaviron on acetylcholinesterase activities in the hippocampus and striatum of adult Wistar rats. In this study, histological and histochemical methods were used to investigate the effects of kolaviron on the histology of the hippocampus and striatum and on acetylcholinesterase activities in these brain regions. We showed that kolaviron produced no neurodegenerative changes in the hippocampus and striatum. Kolaviron did not significantly alter (p
ISSN:0972-7531
0976-3260
DOI:10.5214/ans.0972.7531.200203