Relative Efficacy of AS03-Adjuvanted Pandemic Influenza A(H1N1) Vaccine in Children: Results of a Controlled, Randomized Efficacy Trial

Background. The vaccine efficacy (VE) of 1 or 2 doses of AS03-adjuvanted influenza A(H1N1) vaccine relative to that of 2 doses of nonadjuvanted influenza A(H1N1) vaccine in children 6 months to

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Bibliographische Detailangaben
Veröffentlicht in:	The Journal of infectious diseases 2014-08, Vol.210 (4), p.545-557
Hauptverfasser:	Nolan, Terry, Roy-Ghanta, Sumita, Montellano, May, Weckx, Lily, Ulloa-Gutierrez, Rolando, Lazcano-Ponce, Eduardo, Kerdpanich, Angkool, Safadi, Marco Aurélio Palazzi, Cruz-Valdez, Aurelio, Litao, Sandra, Lim, Fong Seng, de Los Santos, Abiel Mascareñas, Weber, Miguel Angel Rodriguez, Tinoco, Juan-Carlos, Hernandez-de Mezerville, Marcela, Faingezicht, Idis, Kosuwon, Pensri, Lopez, Pio, Borja-Tabora, Charissa, Li, Ping, Durviaux, Serge, Fries, Louis, Dubin, Gary, Breuer, Thomas, Innis, Bruce L., Vaughn, David W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - administration & dosage Antibodies, Viral - immunology Antibody Formation - immunology Applied microbiology Biological and medical sciences Child Child, Preschool Children Dosage Female Fundamental and applied biological sciences. Psychology Grade 3 Humans Immune response Infant Infections Infectious diseases Influenza A Virus, H1N1 Subtype - immunology Influenza vaccines Influenza Vaccines - administration & dosage Influenza Vaccines - immunology Influenza, Human - epidemiology Influenza, Human - immunology Influenza, Human - prevention & control Major and Brief Reports Male Medical sciences Microbiology Miscellaneous Narcolepsy Pandemics Prospective Studies Vaccination Vaccination - methods Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Viral vaccines Virology VIRUSES
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Beschreibung
Zusammenfassung:	Background. The vaccine efficacy (VE) of 1 or 2 doses of AS03-adjuvanted influenza A(H1N1) vaccine relative to that of 2 doses of nonadjuvanted influenza A(H1N1) vaccine in children 6 months to
ISSN:	0022-1899 1537-6613
DOI:	10.1093/infdis/jiu173