PKA-Mediated Phosphorylation of ATR Promotes Recruitment of XPA to UV-Induced DNA Damage

The melanocortin 1 receptor (MC1R), which signals through cAMP, is a melanocytic transmembrane receptor involved in pigmentation, adaptive tanning, and melanoma resistance. We report MC1R-mediated or pharmacologically-induced cAMP signaling promotes nucleotide excision repair (NER) in a cAMP-depende...

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Veröffentlicht in:	Molecular cell 2014-06, Vol.54 (6), p.999-1011
Hauptverfasser:	Jarrett, Stuart G, Horrell, Erin MWolf, Christian, Perry A, Vanover, Jillian C, Boulanger, Mary C, Zou, Yue, D'Orazio, John A
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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