Gamma-secretase subunits associate in intracellular membrane compartments in Arabidopsis thaliana

In animals, gamma-secretase is crucial for regulation of important developmental processes. Here, we show that genes encoding components of this complex are present in Arabidopsis, and the complex undergoes complicated assembly in the endomembrane system. This complex may have some role in autophagy...

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Veröffentlicht in:	Journal of experimental botany 2014, Vol.65 (12), p.3015-3027
Hauptverfasser:	Smolarkiewicz, Michalina, Skrzypczak, Tomasz, Michalak, Michał, Leśniewicz, Krzysztof, Walker, J. Ross, Ingram, Gwyneth, Wojtaszek, Przemysław
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Amyloid Precursor Protein Secretases - chemistry Amyloid Precursor Protein Secretases - genetics Amyloid Precursor Protein Secretases - metabolism Animals Arabidopsis - classification Arabidopsis - enzymology Arabidopsis - genetics Arabidopsis Proteins - chemistry Arabidopsis Proteins - genetics Arabidopsis Proteins - metabolism Arabidopsis thaliana autophagy Biochemistry endomembrane system Fluorescence Gene expression regulation genes Intracellular Membranes - enzymology Life Sciences Molecular Sequence Data Phylogeny Physiological regulation Presenilins Proteins Protoplasts Protoplasts - metabolism RESEARCH PAPER Seedlings Sequence Alignment Vegetal Biology
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Zusammenfassung:	In animals, gamma-secretase is crucial for regulation of important developmental processes. Here, we show that genes encoding components of this complex are present in Arabidopsis, and the complex undergoes complicated assembly in the endomembrane system. This complex may have some role in autophagy.
ISSN:	0022-0957 1460-2431
DOI:	10.1093/jxb/eru147