Indole Alkaloids from Marine Sources as Potential Leads against Infectious Diseases

Indole alkaloids comprise a large and complex class of natural products found in a variety of marine sources. Infectious diseases remain a major threat to public health, and in the absence of long-term protective vaccines, the control of these infectious diseases is based on a small number of chemot...

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Veröffentlicht in:BioMed research international 2014-01, Vol.2014 (2014), p.1-12
Hauptverfasser: França, Paulo H. B., Barbosa, Daniel P., da Silva, Daniel Lira, Ribeiro, Êurica Adélia Nogueira, Santana, Antônio E. G., Santos, Bárbara V. O., Barbosa Filho, José Maria, Quintans, Jullyana S. S., Barreto, Rosana S. S., Quintans Júnior, Lucindo José, Araújo-Júnior, João Xavier
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Sprache:eng
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Zusammenfassung:Indole alkaloids comprise a large and complex class of natural products found in a variety of marine sources. Infectious diseases remain a major threat to public health, and in the absence of long-term protective vaccines, the control of these infectious diseases is based on a small number of chemotherapeutic agents. Furthermore, the emerging resistance against these drugs makes it urgently necessary to discover and develop new, safe and, effective anti-infective agents. In this regard, the aim of this review is to highlight indole alkaloids from marine sources which have been shown to demonstrate activity against infectious diseases.
ISSN:2314-6133
2314-6141
DOI:10.1155/2014/375423