Quality of life, fatigue and local response of patients with unstable spinal bone metastases under radiation therapy--a prospective trial

To evaluate the local response according to stability after radiotherapy (RT) with a special focus on quality-of-life (QoL), fatigue, pain and emotional distress in patients with unstable spinal bone metastases. In this prospective trial, 30 patients were treated from September 2011 until March 2013...

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Veröffentlicht in:	Radiation oncology (London, England) England), 2014-06, Vol.9 (1), p.133-133, Article 133
Hauptverfasser:	Rief, Harald, Heinhold, Maximiliane, Bruckner, Thomas, Schlampp, Ingmar, Förster, Robert, Welzel, Thomas, Bostel, Tilman, Debus, Jürgen, Rieken, Stefan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Awards & honors Bone Neoplasms - complications Bone Neoplasms - radiotherapy Bone Neoplasms - secondary Cancer Cancer therapies Care and treatment Fatigue Fatigue - diagnosis Fatigue - etiology Fatigue - mortality Female Follow-Up Studies Fractures Health aspects Humans Male Medical prognosis Mentoring programs Metastasis Neoplasm Recurrence, Local - complications Neoplasm Recurrence, Local - pathology Neoplasm Recurrence, Local - radiotherapy Neoplasm Staging Neoplasms - complications Neoplasms - pathology Neoplasms - radiotherapy Pain Pain - diagnosis Pain - etiology Pain - mortality Pharmaceutical industry Prognosis Prospective Studies Quality of Life Questionnaires Radiation Radiation Injuries - diagnosis Radiation Injuries - etiology Radiation Injuries - mortality Radiation therapy Radiotherapy Radiotherapy - adverse effects Spinal Neoplasms - complications Spinal Neoplasms - radiotherapy Spinal Neoplasms - secondary Surveys and Questionnaires Survival Rate
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Beschreibung
Zusammenfassung:	To evaluate the local response according to stability after radiotherapy (RT) with a special focus on quality-of-life (QoL), fatigue, pain and emotional distress in patients with unstable spinal bone metastases. In this prospective trial, 30 patients were treated from September 2011 until March 2013. The stability of osteolytic metastases in the thoracic and lumbar spine was evaluated on the basis of the Taneichi-score after three and six months. EORTC QLQ-BM22, EORTC QLQ-FA13, and QSC-R10 were assessed at baseline, and three months after RT. After 3 months, 25% (n = 6) and after 6 months 33.3% (n = 8) were classified as stable. QoL, fatigue, and emotional distress showed no difference over the course. The pain response 3 months after RT showed a significant difference (p
ISSN:	1748-717X 1748-717X
DOI:	10.1186/1748-717X-9-133