Mistletoe: From Basic Research to Clinical Outcomes in Cancer and Other Indications

Recent years have seen growth in the number and quality of clinical research studies on mistletoe therapy reporting improved patient outcomes, including studies of its coadministration alongside chemotherapy to reduce adverse effects and to improve quality of life in breast cancer, ovarian cancer, and lung cancer patients [11, 12]. In a Serbian randomized-controlled study, W. Tröger and colleagues measured the impact of concomitant mistletoe treatment with adjuvant chemotherapy on health-related quality of life in breast cancer patients. [11] V. F. Semiglazov, V. V. Stepula, A. Dudov, J. Schnitker, U. Mengs, "Quality of life is improved in breast cancer patients by standardised mistletoe extract PS76A2 during chemotherapy and follow-up: A randomised, placebo-controlled, double-blind, multicentre clinical trial," Anticancer Research, vol. 26 no. 2, pp. 1519-1529, 2006.