A chemical approach to ＂rewire＂ neural progenitor cells

Generation of neural progenitor cells （NPCs） from pluripotent stem cells including ESCs and iPSCs and derivation of NPCs from somatic tissues have been considered promising approaches that could be used therapeutically to restore function in patients suffering neurodegenerative diseases. A new study...

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Veröffentlicht in:	Cell research 2014-06, Vol.24 (6), p.641-642
Hauptverfasser:	Wu, Min-Zu, Li, Mo, Liu, Guang-Hui, Belmonte, Juan Carlos Izpisua
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/1407 631/378/2571/2579 631/61/490 631/92 Animals Biomedical and Life Sciences Cell Biology Cell Hypoxia Enzyme Inhibitors - pharmacology Humans Hypoxia Life Sciences Neural Stem Cells - drug effects Pyrazoles - pharmacology Pyridines - pharmacology Pyrimidines - pharmacology Research Highlight Stem cells Valproic Acid - pharmacology 化学多能干细胞恢复功能祖细胞神经退行性疾病细胞组织胚胎干细胞连接
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Zusammenfassung:	Generation of neural progenitor cells （NPCs） from pluripotent stem cells including ESCs and iPSCs and derivation of NPCs from somatic tissues have been considered promising approaches that could be used therapeutically to restore function in patients suffering neurodegenerative diseases. A new study published in CellResearch shows, for the first time,
ISSN:	1001-0602 1748-7838
DOI:	10.1038/cr.2014.51