Working together: basal ganglia pathways in action selection

Working together: basal ganglia pathways in action selection

Jin, Tecuapetla, and Costa combined in vivo electrophysiology with optogenetic-identification to examine firing in multiple basal ganglia nuclei during rapid motor sequences. Their results support a model of basal ganglia function in which co-activation of the direct and indirect pathways facilitate...

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Veröffentlicht in:Trends in neurosciences (Regular ed.) 2014-06, Vol.37 (6), p.301-303
Hauptverfasser: Friend, Danielle M, Kravitz, Alexxai V
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Basal Ganglia - physiology
Brain - physiology
Learning - physiology
Mice
Motor Activity - physiology
Neural Pathways - physiology
Neurology
Optogenetics
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Zusammenfassung:Jin, Tecuapetla, and Costa combined in vivo electrophysiology with optogenetic-identification to examine firing in multiple basal ganglia nuclei during rapid motor sequences. Their results support a model of basal ganglia function in which co-activation of the direct and indirect pathways facilitate appropriate, while inhibiting competing, motor programs.
ISSN:0166-2236
1878-108X
DOI:10.1016/j.tins.2014.04.004