Topography Prediction of Helical Transmembrane Proteins by a New Modification of the Sliding Window Method

Protein functions are specified by its three-dimensional structure, which is usually obtained by X-ray crystallography. Due to difficulty of handling membrane proteins experimentally to date the structure has only been determined for a very limited part of membrane proteins (

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Bibliographische Detailangaben
Veröffentlicht in:	BioMed research international 2014-01, Vol.2014 (2014), p.1-9
Hauptverfasser:	Simakova, Maria N., Simakov, Nikolai N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Computer Simulation Crystallography, X-Ray - methods Fourier transforms Genomes Hydrophobic and Hydrophilic Interactions Membrane proteins Membrane Proteins - chemistry Physiological aspects Protein Structure, Secondary Protein Structure, Tertiary Proteins Statistical methods X-ray crystallography
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Beschreibung
Zusammenfassung:	Protein functions are specified by its three-dimensional structure, which is usually obtained by X-ray crystallography. Due to difficulty of handling membrane proteins experimentally to date the structure has only been determined for a very limited part of membrane proteins (
ISSN:	2314-6133 2314-6141
DOI:	10.1155/2014/921218