Lipid tucaresol as an adjuvant for methamphetamine vaccine development

The immunopotentiator tucaresol was modified for incorporation into liposomes, where it was found to be a superior adjuvant to MPLA for vaccination against methamphetamine.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2014-04, Vol.50 (31), p.4079-4081
Hauptverfasser:	Collins, K C, Schlosburg, J E, Lockner, J W, Bremer, P T, Ellis, B A, Janda, K D
Format:	Artikel
Sprache:	eng
Schlagworte:	adjuvants Adjuvants, Immunologic - administration & dosage Adjuvants, Immunologic - chemistry Animals Antibodies - blood Antibodies - immunology Benzaldehydes - administration & dosage Benzaldehydes - chemistry Benzoates - administration & dosage Benzoates - chemistry chemical reactions Haptens - administration & dosage Haptens - chemistry immunostimulants Lipid A - administration & dosage Lipid A - chemistry lipids liposomes (artificial) Methamphetamine - immunology methamphetamines Mice Substance-Related Disorders - prevention & control vaccination vaccine development Vaccines - administration & dosage Vaccines - chemistry
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Beschreibung
Zusammenfassung:	The immunopotentiator tucaresol was modified for incorporation into liposomes, where it was found to be a superior adjuvant to MPLA for vaccination against methamphetamine.
ISSN:	1359-7345 1364-548X 1364-548X
DOI:	10.1039/c4cc00682h