Midline frontal cortex low-frequency activity drives subthalamic nucleus oscillations during conflict

Making the right decision from conflicting information takes time. Recent computational, electrophysiological, and clinical studies have implicated two brain areas as being crucial in assuring sufficient time is taken for decision-making under conditions of conflict: the medial prefrontal cortex and...

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Veröffentlicht in:	The Journal of neuroscience 2014-05, Vol.34 (21), p.7322-7333
Hauptverfasser:	Zavala, Baltazar A, Tan, Huiling, Little, Simon, Ashkan, Keyoumars, Hariz, Marwan, Foltynie, Thomas, Zrinzo, Ludvic, Zaghloul, Kareem A, Brown, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Brain Mapping Brain Waves - physiology Choice Behavior - physiology Conflict, Psychological Deep Brain Stimulation - methods Efferent Pathways - physiology Electroencephalography Female Frontal Lobe - physiology Humans Magnetic Resonance Imaging Male Middle Aged Parkinson Disease - physiopathology Parkinson Disease - therapy Subthalamic Nucleus - physiology
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Beschreibung
Zusammenfassung:	Making the right decision from conflicting information takes time. Recent computational, electrophysiological, and clinical studies have implicated two brain areas as being crucial in assuring sufficient time is taken for decision-making under conditions of conflict: the medial prefrontal cortex and the subthalamic nucleus (STN). Both structures exhibit an elevation of activity at low frequencies (
ISSN:	0270-6474 1529-2401
DOI:	10.1523/jneurosci.1169-14.2014