In-vivo anti-inflammatory and anti-pyretic activities of Manilkara zapota leaves in albino Wistar rats
To screen ethanolic extracts of Manilkara zapota leaves (Family: Sapotaceae) and its different solvent soluble fractions for possible anti-inflammatory, anti-pyretic activities in experimental albino Wistar rats. Anti-inflammatory activity was evaluated by carrageenan induced paw edema method; anti-...
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| Veröffentlicht in: | Asian Pacific journal of tropical disease 2013-08, Vol.3 (4), p.301-307 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | To screen ethanolic extracts of Manilkara zapota leaves (Family: Sapotaceae) and its different solvent soluble fractions for possible anti-inflammatory, anti-pyretic activities in experimental albino Wistar rats.
Anti-inflammatory activity was evaluated by carrageenan induced paw edema method; anti-pyretic potential was determined by yeast-induced pyrexia method in albino Wistar rats.
In evaluation of anti-inflammatory activity the crude ethanolic (300 mg/kg) and ethyl acetate extract (300 mg/kg) showed significant inhibition of paw edema by 91.98% and 92.41% (P |
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| ISSN: | 2222-1808 2222-1808 |
| DOI: | 10.1016/S2222-1808(13)60073-0 |