Genetics of Type 2 Diabetes : Insights into the Pathogenesis and Its Clinical Application

Genetics of Type 2 Diabetes : Insights into the Pathogenesis and Its Clinical Application

With rapidly increasing prevalence, diabetes has become one of the major causes of mortality worldwide. According to the latest studies, genetic information makes substantial contributions towards the prediction of diabetes risk and individualized antidiabetic treatment. To date, approximately 70 su...

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Veröffentlicht in:BioMed research international 2014-01, Vol.2014 (2014), p.1-15
Hauptverfasser: Sun, Xue, Yu, Weihui, Hu, Cheng
Format: Artikel
Sprache:eng
Schlagworte:
Chromosomes
Diabetes Mellitus, Type 2 - genetics
Genes
Genetic Loci
Genetic Predisposition to Disease
Genomics
Humans
Insulin resistance
Metabolic disorders
Pharmacogenetics
Research - trends
Review
Rodents
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Zusammenfassung:With rapidly increasing prevalence, diabetes has become one of the major causes of mortality worldwide. According to the latest studies, genetic information makes substantial contributions towards the prediction of diabetes risk and individualized antidiabetic treatment. To date, approximately 70 susceptibility genes have been identified as being associated with type 2 diabetes (T2D) at a genome-wide significant level (P
ISSN:2314-6133
2314-6141
DOI:10.1155/2014/926713