Neurodevelopmental Outcome of Infants With Unilateral or Bilateral Periventricular Hemorrhagic Infarction

Neurodevelopmental Outcome of Infants With Unilateral or Bilateral Periventricular Hemorrhagic Infarction

Periventricular hemorrhagic infarction (PVHI) is a major contributing factor to poor neurodevelopmental outcomes in preterm infants. We hypothesized that surviving infants with unilateral PVHI would have more favorable outcomes than those with bilateral PVHI. This was a multicenter, retrospective st...

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Veröffentlicht in:Pediatrics (Evanston) 2009-12, Vol.124 (6), p.e1153-e1160
Hauptverfasser: Maitre, Nathalie L, Marshall, Diane D, Price, Wayne A, Slaughter, James C, O'Shea, Thomas M, Maxfield, Charles, Goldstein, Ricki F
Format: Artikel
Sprache:eng
Schlagworte:
Babies
Brain
Brain Damage, Chronic - diagnosis
Brain Damage, Chronic - mortality
Cerebral Hemorrhage - diagnosis
Cerebral Infarction - diagnosis
Cerebral Infarction - mortality
Cerebral Ventricles - blood supply
Child, Preschool
Clinical medicine
Clinical outcomes
Cohort Studies
Developmental Disabilities - diagnosis
Developmental Disabilities - mortality
Dominance, Cerebral - physiology
Echoencephalography
Female
Humans
Infant, Newborn
Infant, Premature, Diseases - diagnosis
Leukomalacia, Periventricular - diagnosis
Leukomalacia, Periventricular - mortality
Magnetic Resonance Imaging
Male
Medical research
Neurologic Examination
Neurology
Neuropsychological Tests
North Carolina
Pediatrics
Probability
Retinopathy of Prematurity - diagnosis
Retrospective Studies
Risk Assessment
Survival Rate
Tomography, X-Ray Computed
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Zusammenfassung:Periventricular hemorrhagic infarction (PVHI) is a major contributing factor to poor neurodevelopmental outcomes in preterm infants. We hypothesized that surviving infants with unilateral PVHI would have more favorable outcomes than those with bilateral PVHI. This was a multicenter, retrospective study of infants who were admitted to 3 NICUs in North Carolina from 1998 to 2004. The clinical course and late neuroimaging studies and neurodevelopmental outcomes of 69 infants who weighed
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.2009-0953