Interleukin-6 and Vitamin D Status during High-Intensity Resistance Training in Patients with Chronic Kidney Disease

Background. The aim of this study was to investigate IL-6 and 25-hydroxyvitamin D (25-OH D) associations with muscle size and muscle function in dialysis patients. Methods. Patients were included in a 16-week control period followed by 16 weeks of high-intensity resistance training thrice weekly. IL...

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Veröffentlicht in:	BioMed research international 2014-01, Vol.2014 (2014), p.1-8
Hauptverfasser:	Eidemak, Inge, Eiken, Pia, Andersen, Jesper L., Harrison, Adrian P., Molsted, Stig
Format:	Artikel
Sprache:	eng
Schlagworte:	Alfacalcidol Calcifediol Clinical Study Female Health aspects Hemodialysis Humans Interleukin-6 - blood Interleukins Male Middle Aged Mortality Muscle Strength Muscle, Skeletal - pathology Muscle, Skeletal - physiopathology Muscles Nephritis - complications Nephritis - physiopathology Nephritis - prevention & control Older people Organ Size Peritoneal dialysis Physical fitness Renal Insufficiency, Chronic - complications Renal Insufficiency, Chronic - physiopathology Renal Insufficiency, Chronic - therapy Resistance Training - methods Treatment Outcome Vitamin D Vitamin D - blood
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Zusammenfassung:	Background. The aim of this study was to investigate IL-6 and 25-hydroxyvitamin D (25-OH D) associations with muscle size and muscle function in dialysis patients. Methods. Patients were included in a 16-week control period followed by 16 weeks of high-intensity resistance training thrice weekly. IL-6 and 25-OH D were analysed after an over-night fast. Muscle fibre size was analysed in biopsies from m. vastus lateralis. Muscle power was tested using a Leg Extensor Power Rig. Results. Patients (n=36) with IL-6 ≥ 6.49 pg/ml (median) were older and had decreased muscle power and a reduced protein intake (P
ISSN:	2314-6133 2314-6141
DOI:	10.1155/2014/176190