The insulin-like growth factor 2 (IGF2) mRNA-binding protein p62/IGF2BP2-2 as a promoter of NAFLD and HCC?

Non-alcoholic fatty liver disease (NAFLD) represents the most common hepatic manifestation of chronic liver diseases in developed countries.

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Bibliographische Detailangaben
Veröffentlicht in:	Gut 2014-05, Vol.63 (5), p.861-863
Hauptverfasser:	Simon, Yvette, Kessler, Sonja M, Bohle, Rainer M, Haybaeck, Johannes, Kiemer, Alexandra K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers - metabolism Biomarkers, Tumor - metabolism Carcinoma, Hepatocellular - etiology Carcinoma, Hepatocellular - metabolism Chemokine CCL2 - metabolism Fatty Liver - complications Fatty Liver - metabolism Gene expression Insulin-like growth factors Kinases Liver Neoplasms - etiology Liver Neoplasms - metabolism Mice Non-alcoholic Fatty Liver Disease PostScript Proteins RNA-Binding Proteins - metabolism Rodents Transcription factors Transcription Factors - metabolism Transgenic animals
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Beschreibung
Zusammenfassung:	Non-alcoholic fatty liver disease (NAFLD) represents the most common hepatic manifestation of chronic liver diseases in developed countries.
ISSN:	0017-5749 1468-3288
DOI:	10.1136/gutjnl-2013-305736