Molecular epidemiology of merkel cell polyomavirus: evidence for geographically related variant genotypes

Merkel cell polyomavirus (MCPyV) is linked to a cutaneous cancer mainly occurring in Caucasians. DNA from skin swabs of 255 adults, originating from the 5 continents, were subjected to MCPyV PCRs. Phylogenetic analyses demonstrate the existence of 5 major geographically related MCPyV genotypes (Euro...

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Veröffentlicht in:	Journal of clinical microbiology 2014-05, Vol.52 (5), p.1687-1690
Hauptverfasser:	Martel-Jantin, Claire, Filippone, Claudia, Tortevoye, Patricia, Afonso, Philippe V, Betsem, Edouard, Descorps-Declere, Stéphane, Nicol, Jérôme T J, Touzé, Antoine, Coursaget, Pierre, Crouzat, Maryse, Berthet, Nicolas, Cassar, Olivier, Gessain, Antoine
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged, 80 and over Carcinoma, Merkel Cell - epidemiology Carcinoma, Merkel Cell - virology DNA, Viral - genetics Female Genotype Humans Life Sciences Male Merkel cell polyomavirus - genetics Middle Aged Molecular Epidemiology Molecular Sequence Data Phylogeny Polymerase Chain Reaction - methods Polyomavirus Polyomavirus Infections - epidemiology Polyomavirus Infections - virology Tumor Virus Infections - epidemiology Tumor Virus Infections - virology Virology Young Adult
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Zusammenfassung:	Merkel cell polyomavirus (MCPyV) is linked to a cutaneous cancer mainly occurring in Caucasians. DNA from skin swabs of 255 adults, originating from the 5 continents, were subjected to MCPyV PCRs. Phylogenetic analyses demonstrate the existence of 5 major geographically related MCPyV genotypes (Europe/North America, Africa [sub-Saharan], Oceania, South America, and Asia/Japan).
ISSN:	0095-1137 1098-660X
DOI:	10.1128/JCM.02348-13