High-sensitivity Analytical Approaches for the Structural Characterization of Glycoproteins
High-sensitivity bioanalytical methods were used to detail the structural characterization of glycoproteins. Recombinant antibody glycans can be analyzed through high-performance liquid chromatography, capillary electrophoresis with laser-induced fluorescence and capillary electrophoresis-mass spect...
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| Veröffentlicht in: | Chemical reviews 2013-04, Vol.113 (4), p.2668-2732 |
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| container_end_page | 2732 |
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| container_title | Chemical reviews |
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| creator | Alley, William R Mann, Benjamin F Novotny, Milos V |
| description | High-sensitivity bioanalytical methods were used to detail the structural characterization of glycoproteins. Recombinant antibody glycans can be analyzed through high-performance liquid chromatography, capillary electrophoresis with laser-induced fluorescence and capillary electrophoresis-mass spectrometry. |
| doi_str_mv | 10.1021/cr3003714 |
| format | Article |
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Recombinant antibody glycans can be analyzed through high-performance liquid chromatography, capillary electrophoresis with laser-induced fluorescence and capillary electrophoresis-mass spectrometry.</description><subject>Antibodies</subject><subject>Capillarity</subject><subject>Chromatography</subject><subject>Chromatography, Liquid</subject><subject>Computational Biology</subject><subject>Electrophoresis, Capillary</subject><subject>Fluorescence</subject><subject>Glycomics</subject><subject>Glycopeptides - chemistry</subject><subject>Glycopeptides - metabolism</subject><subject>Glycoprotein</subject><subject>Glycoproteins</subject><subject>Glycoproteins - analysis</subject><subject>Glycoproteins - isolation & purification</subject><subject>Glycoproteins - metabolism</subject><subject>Glycosylation</subject><subject>Mass Spectrometry</subject><subject>Mathematical analysis</subject><subject>Polysaccharides - chemistry</subject><subject>Polysaccharides - isolation & purification</subject><subject>Recombinant</subject><subject>Sialic Acids - chemistry</subject><subject>Spectrometry</subject><subject>Structural analysis</subject><issn>0009-2665</issn><issn>1520-6890</issn><issn>1520-6890</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkctKAzEUhoMoWi8LX0AGRNDFaC6TTLIRSvEGggt15SJkYsaJTCc1yRTq05vSWqpuXB1Ozpf_XH4ADhE8RxCjC-0JhKRExQYYIIphzriAm2AAIRQ5ZozugN0Q3lNKKS63wQ4mlCCE4QC83Nq3Jg-mCzbaqY2zbNipdhatVm02nEy8U7oxIaudz2Jjssfoex17n6qjRnmlo_H2U0XruszV2U070y59isZ2YR9s1aoN5mAZ98Dz9dXT6Da_f7i5Gw3vc0UJjjkrRE0ral5hqXh6qQrES2y44IyUyvAKG1QVsNZlVeuCzBkuNMQKsRS4InvgcqE76auxedWmi2k-OfF2rPxMOmXlz0pnG_nmppIIgUWJk8DpUsC7j96EKMc2aNO2qjOuDzI1wgQxyP-BEsxQgRjlCT3-hb673qfrzilWUiQYn1NnC0p7F4I39WpuBOXcXblyN7FH64uuyG87E3CyAJQOa93-CH0B-cyrrg</recordid><startdate>20130410</startdate><enddate>20130410</enddate><creator>Alley, William R</creator><creator>Mann, Benjamin F</creator><creator>Novotny, Milos V</creator><general>American Chemical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>7X8</scope><scope>7U5</scope><scope>L7M</scope><scope>5PM</scope></search><sort><creationdate>20130410</creationdate><title>High-sensitivity Analytical Approaches for the Structural Characterization of Glycoproteins</title><author>Alley, William R ; Mann, Benjamin F ; Novotny, Milos V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a532t-649f5b5ed07a8532b41872e898637ae8b2e1b40fc7bfc43a85389c02a169c08a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Antibodies</topic><topic>Capillarity</topic><topic>Chromatography</topic><topic>Chromatography, Liquid</topic><topic>Computational Biology</topic><topic>Electrophoresis, Capillary</topic><topic>Fluorescence</topic><topic>Glycomics</topic><topic>Glycopeptides - chemistry</topic><topic>Glycopeptides - metabolism</topic><topic>Glycoprotein</topic><topic>Glycoproteins</topic><topic>Glycoproteins - analysis</topic><topic>Glycoproteins - isolation & purification</topic><topic>Glycoproteins - metabolism</topic><topic>Glycosylation</topic><topic>Mass Spectrometry</topic><topic>Mathematical analysis</topic><topic>Polysaccharides - chemistry</topic><topic>Polysaccharides - isolation & purification</topic><topic>Recombinant</topic><topic>Sialic Acids - chemistry</topic><topic>Spectrometry</topic><topic>Structural analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Alley, William R</creatorcontrib><creatorcontrib>Mann, Benjamin F</creatorcontrib><creatorcontrib>Novotny, Milos V</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>MEDLINE - Academic</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Chemical reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alley, William R</au><au>Mann, Benjamin F</au><au>Novotny, Milos V</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>High-sensitivity Analytical Approaches for the Structural Characterization of Glycoproteins</atitle><jtitle>Chemical reviews</jtitle><addtitle>Chem. 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| identifier | ISSN: 0009-2665 |
| ispartof | Chemical reviews, 2013-04, Vol.113 (4), p.2668-2732 |
| issn | 0009-2665 1520-6890 1520-6890 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3992972 |
| source | MEDLINE; ACS Publications |
| subjects | Antibodies Capillarity Chromatography Chromatography, Liquid Computational Biology Electrophoresis, Capillary Fluorescence Glycomics Glycopeptides - chemistry Glycopeptides - metabolism Glycoprotein Glycoproteins Glycoproteins - analysis Glycoproteins - isolation & purification Glycoproteins - metabolism Glycosylation Mass Spectrometry Mathematical analysis Polysaccharides - chemistry Polysaccharides - isolation & purification Recombinant Sialic Acids - chemistry Spectrometry Structural analysis |
| title | High-sensitivity Analytical Approaches for the Structural Characterization of Glycoproteins |
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