Carotid Plaque Neovascularization and Hemorrhage Detected by MR Imaging are Associated with Recent Cerebrovascular Ischemic Events

Pathologic studies suggest that neovascularization and hemorrhage are important features of plaque vulnerability for disruption. Our aim was to determine the associations of these features in carotid plaques with previous cerebrovascular ischemic events by using high-resolution CE-MRI. Forty-seven p...

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Veröffentlicht in:	American journal of neuroradiology : AJNR 2012-04, Vol.33 (4), p.755-760
Hauptverfasser:	QIAO, Y, ETESAMI, M, ASTOR, B. C, ZEILER, S. R, TROUT, H. H, WASSERMAN, B. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aged Aged, 80 and over Biological and medical sciences Brain Ischemia - complications Brain Ischemia - pathology Cardiovascular diseases Carotid Stenosis - complications Carotid Stenosis - pathology Cerebrospinal fluid. Spinal cord. Spinal roots. Spinal nerves Computed tomography Extracranial Vascular Female Hemorrhage Hemorrhage - complications Hemorrhage - pathology Humans Investigative techniques, diagnostic techniques (general aspects) Ischemia Magnetic Resonance Angiography - methods Magnetic Resonance Imaging Male Medical sciences Middle Aged Neovascularization, Pathologic - complications Neovascularization, Pathologic - pathology Nervous system Neuroimaging Neurosurgery Plaques Radiodiagnosis. Nmr imagery. Nmr spectrometry Reproducibility of Results Risk factors Sensitivity and Specificity Sex Stenosis Stroke Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases vascularization
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Zusammenfassung:	Pathologic studies suggest that neovascularization and hemorrhage are important features of plaque vulnerability for disruption. Our aim was to determine the associations of these features in carotid plaques with previous cerebrovascular ischemic events by using high-resolution CE-MRI. Forty-seven patients (36 men; mean age 72.5 ± 10 years) underwent CE-MRI and MRA examinations for carotid plaque at 3T. IPH presence was recorded. Neovascularity was categorized by the degree of adventitial enhancement (0, absent; 1,
ISSN:	0195-6108 1936-959X
DOI:	10.3174/ajnr.A2863