Circadian timekeeping and output mechanisms in animals
Highlights • Work on circadian period determination and output gene regulation are reviewed. • Clock protein glycosylation, ubiquitylation and translation influence 24 hours periodicity. • Whole genome approaches reveal novel features of clock-controlled transcription. • Rhythms in post-transcriptio...
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Veröffentlicht in: | Current opinion in neurobiology 2013-10, Vol.23 (5), p.724-731 |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Highlights • Work on circadian period determination and output gene regulation are reviewed. • Clock protein glycosylation, ubiquitylation and translation influence 24 hours periodicity. • Whole genome approaches reveal novel features of clock-controlled transcription. • Rhythms in post-transcriptional regulators imply more pervasive circadian expression. |
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ISSN: | 0959-4388 1873-6882 |
DOI: | 10.1016/j.conb.2013.02.018 |