Effects of D-003, a mixture of high-molecular-weight sugar cane wax acids, on lipid peroxidation markers in older individuals: A randomized, double-blind, placebo-controlled study

Abstract Background: Aging is associated with increased lipid peroxidation (LP). D-003, a mixture of long-chain aliphatic primary acids purified from sugar cane wax, has been found to inhibit LP in experimental models and in healthy subjects. Objectives: The aim of this study was to assess the effec...

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Veröffentlicht in:Current therapeutic research 2008-02, Vol.69 (1), p.36-48
Hauptverfasser: Pérez, Yohani, PhD, Menéndez, Roberto, PhD, Ferrer, José I., MD, PhD, Lopez, Ernesto, MD, Castaño, Gladys, MD, PhD, Fernández, Julio, PhD, Ferreiro, Rosa M., PhD, Fernández, Lilia, PhD, Mendoza, Sarahí, PhD, González, Rosa, BA, Mesa, Melbis, BA
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Sprache:eng
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Zusammenfassung:Abstract Background: Aging is associated with increased lipid peroxidation (LP). D-003, a mixture of long-chain aliphatic primary acids purified from sugar cane wax, has been found to inhibit LP in experimental models and in healthy subjects. Objectives: The aim of this study was to assess the effects of D-003 on LP markers and the lipid profile of older individuals. Methods: This randomized, double-blind, placebo-controlled study was conducted at the Plaza Veterans' House, Havana City, Cuba. Male and female patients aged ≥60 years with total cholesterol values of
ISSN:0011-393X
1879-0313
DOI:10.1016/j.curtheres.2008.01.001