Unique Contribution of Fatigue to Disability in Community-Dwelling Adults With Traumatic Brain Injury

Abstract Objective To examine the unique contribution of fatigue to self-reported disability in community-dwelling adults with traumatic brain injury (TBI). Design A cross-sectional cohort design. Setting Community dwellings. Participants Adults (N=50) with a history of mild to severe TBI were assessed. Intervention Not applicable. Main Outcome Measures This study assessed the contribution of fatigue (Modified Fatigue Impact Scale) to disability (Mayo-Portland Adaptability Inventory), controlling for executive functions (Frontal Systems Behavior Scale), depression status (major depression in partial remission/current major depression/depressive symptoms or no history of depression), and initial injury severity (uncomplicated mild, complicated mild, moderate, or severe). Results Fatigue was found to contribute uniquely to the variance in self-reported disability (β=.47, P