The case for Zostavax vaccination in systemic lupus erythematosus

The case for Zostavax vaccination in systemic lupus erythematosus

Individuals with autoimmune diseases, including systemic lupus erythematosus (SLE), appear to be at increased risk for HZ, possibly due to inherent immune dysregulation associated with the disease, immunosuppressive therapies, or a combination of the two. [...]the OKA vaccine strain was attenuated b...

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Veröffentlicht in:Vaccine 2013-08, Vol.31 (36), p.3640-3643
Hauptverfasser: Cogman, Abigail R, Chakravarty, Eliza F
Format: Artikel
Sprache:eng
Schlagworte:
Activities of daily living
Age
Allergy and Immunology
Autoimmune diseases
Biomedical research
Contraindications
Disease
Drug dosages
Herpes zoster
Herpes Zoster - complications
Herpes Zoster Vaccine - adverse effects
Humans
Infection
Lupus
Lupus Erythematosus, Systemic - complications
Older people
Patients
Practice Guidelines as Topic
Quality of life
Rheumatology
Shingles
Studies
Systemic lupus erythematosus
Vaccination - adverse effects
Vaccine
Vaccines
Varicella zoster virus
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Zusammenfassung:Individuals with autoimmune diseases, including systemic lupus erythematosus (SLE), appear to be at increased risk for HZ, possibly due to inherent immune dysregulation associated with the disease, immunosuppressive therapies, or a combination of the two. [...]the OKA vaccine strain was attenuated by serial passages in cell cultures and is avirulant as compared to wild type strains.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2013.05.085