Transneuronal tracing with neurotropic viruses reveals network macroarchitecture

Transneuronal tracing with neurotropic viruses reveals network macroarchitecture

Highlights ► Retrograde transneuronal transport of rabies virus can trace circuits of three or more neurons. ► Rabies travels through multi-synaptic pathways within motor, cognitive and autonomic circuits. ► Tracing with rabies has revealed that the cerebellum and basal ganglia are interconnected....

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Veröffentlicht in:Current opinion in neurobiology 2013-04, Vol.23 (2), p.245-249
Hauptverfasser: Dum, Richard P, Strick, Peter L
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Autonomic nervous system
Brain - physiology
Humans
Nerve Net - physiology
Neural Pathways - physiology
Neurology
Polysaccharides - genetics
Polysaccharides - metabolism
Primates
Psychiatry
Rabies virus - physiology
Synapses - physiology
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Zusammenfassung:Highlights ► Retrograde transneuronal transport of rabies virus can trace circuits of three or more neurons. ► Rabies travels through multi-synaptic pathways within motor, cognitive and autonomic circuits. ► Tracing with rabies has revealed that the cerebellum and basal ganglia are interconnected.
ISSN:0959-4388
1873-6882
DOI:10.1016/j.conb.2012.12.002