Prognostic Impact of Radiation Therapy to the Primary Tumor in Patients With Non-small Cell Lung Cancer and Oligometastasis at Diagnosis

Purpose We investigated prognostic factors associated with survival in patients with non-small cell lung cancer (NSCLC) and oligometastatic disease at diagnosis, particularly the influence of local treatment to the primary site on prognosis. Methods and Materials From January 2000 through June 2011,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2012-09, Vol.84 (1), p.e61-e67
Hauptverfasser:	Lopez Guerra, Jose Luis, MD, Gomez, Daniel, MD, Zhuang, Yan, MD, Hong, David S., BA, Heymach, John V., MD, PhD, Swisher, Stephen G., MD, Lin, Steven H., MD, PhD, Komaki, Ritsuko, MD, Cox, James D., MD, Liao, Zhongxing, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - mortality Adenocarcinoma - pathology Adenocarcinoma - radiotherapy Adenocarcinoma - therapy Adult Aged Aged, 80 and over Analysis of Variance BRAIN Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - pathology Carcinoma, Non-Small-Cell Lung - radiotherapy Carcinoma, Non-Small-Cell Lung - secondary CARCINOMAS DIAGNOSIS Female HEALTH HAZARDS Hematology, Oncology and Palliative Medicine HISTOLOGY Humans Karnofsky Performance Status Lung Neoplasms - mortality Lung Neoplasms - pathology Lung Neoplasms - radiotherapy LUNGS Male METASTASES Middle Aged MULTIVARIATE ANALYSIS Neoplasm Staging PATIENTS Prognosis RADIATION DOSES Radiology RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Radiotherapy Dosage Risk Factors Tumor Burden
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Purpose We investigated prognostic factors associated with survival in patients with non-small cell lung cancer (NSCLC) and oligometastatic disease at diagnosis, particularly the influence of local treatment to the primary site on prognosis. Methods and Materials From January 2000 through June 2011, 78 consecutive patients with oligometastatic NSCLC (80 ( P =.007), had a gross tumor volume ≤124 cm3 ( P =.002), had adenocarcinoma histology ( P =.002), or had no history of respiratory disease ( P =.016). On multivariate analysis, radiation dose, performance status, and tumor volume retained significance ( P =.004, P =.006, and P
ISSN:	0360-3016 1879-355X
DOI:	10.1016/j.ijrobp.2012.02.054