A “Big Data” View of the Tumor “Immunome”

A “Big Data” View of the Tumor “Immunome”

Tumors are complex masses containing not just neoplastic cells but also stromal cells, neovasculature, and a gamut of immune cells. In this issue, Bindea et al. (2013) identify a surprising new “immune landscape” associated with prolonged disease-free survival.

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Bibliographische Detailangaben
Veröffentlicht in:Immunity (Cambridge, Mass.) Mass.), 2013-10, Vol.39 (4), p.631-632
1. Verfasser: Restifo, Nicholas P.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
B-Lymphocytes - immunology
Carcinoma - immunology
Chemokine CXCL13 - immunology
Colorectal cancer
Colorectal Neoplasms - immunology
Humans
Immune system
Immunotherapy
Interleukins - immunology
Neoplasm Recurrence, Local - immunology
Rodents
T-Lymphocytes, Helper-Inducer - immunology
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Beschreibung
Zusammenfassung:Tumors are complex masses containing not just neoplastic cells but also stromal cells, neovasculature, and a gamut of immune cells. In this issue, Bindea et al. (2013) identify a surprising new “immune landscape” associated with prolonged disease-free survival.
ISSN:1074-7613
1097-4180
DOI:10.1016/j.immuni.2013.10.002