Implications of C1q/TNF-related protein-3 (CTRP-3) and progranulin in patients with acute coronary syndrome and stable angina pectoris

C1q/TNF-related protein-3 (CTRP-3), an adiponectin paralog, and progranulin were recently identified as novel adipokines which may link obesity with glucose dysregulation and subclinical inflammation. We analyzed the relationship between CTRP-3, progranulin and coronary artery disease (CAD) in Korea...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cardiovascular Diabetology 2014-01, Vol.13 (1), p.14-14, Article 14
Hauptverfasser:	Choi, Kyung Mook, Hwang, Soon Young, Hong, Ho Chel, Choi, Hae Yoon, Yoo, Hye Jin, Youn, Byung-Soo, Baik, Sei Hyun, Seo, Hong Seog
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Coronary Syndrome - blood Acute Coronary Syndrome - diagnosis Acute coronary syndromes Aged Angina, Stable - blood Angina, Stable - diagnosis Biomarkers - blood Cardiac patients Cardiovascular disease Care and treatment Comparative analysis Coronary vessels Cross-Sectional Studies Diabetes Female Health aspects Heart attacks Humans Insulin resistance Intercellular Signaling Peptides and Proteins - blood Male Middle Aged Original Investigation Patient outcomes Proteins Risk factors Studies Tumor Necrosis Factors - blood Type 2 diabetes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	C1q/TNF-related protein-3 (CTRP-3), an adiponectin paralog, and progranulin were recently identified as novel adipokines which may link obesity with glucose dysregulation and subclinical inflammation. We analyzed the relationship between CTRP-3, progranulin and coronary artery disease (CAD) in Korean men and women. Circulating CTRP-3 and progranulin levels were examined in 362 Korean adults with acute coronary syndrome (ACS, n = 69), stable angina pectoris (SAP, n = 85), and control subjects (n = 208) along with various kinds of cardiometabolic risk factors. CTRP-3 concentrations were significantly decreased in patients with ACS or SAP compared to control subjects (P
ISSN:	1475-2840 1475-2840
DOI:	10.1186/1475-2840-13-14