Mechanisms underlying obesity resistance associated with high spontaneous physical activity
Highlights • OX1R and DA1R antagonists reduced OXA-induced SPA more effectively in lean rats. • OXA increased arousal equally in lean and obese rodents. • OR rats ran more and wheel running was directly related to 24-h SPA levels.
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| Veröffentlicht in: | Neuroscience 2014-01, Vol.256, p.91-100 |
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| container_title | Neuroscience |
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| creator | Teske, J.A Billington, C.J Kotz, C.M |
| description | Highlights • OX1R and DA1R antagonists reduced OXA-induced SPA more effectively in lean rats. • OXA increased arousal equally in lean and obese rodents. • OR rats ran more and wheel running was directly related to 24-h SPA levels. |
| doi_str_mv | 10.1016/j.neuroscience.2013.10.028 |
| format | Article |
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| ispartof | Neuroscience, 2014-01, Vol.256, p.91-100 |
| issn | 0306-4522 1873-7544 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3888868 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Age Factors Animals Benzazepines - pharmacology Benzoxazoles - pharmacology Biological and medical sciences Body Weight - drug effects Dopamine Antagonists - pharmacology Eating - drug effects Electromyography Eye Movements - drug effects Fundamental and applied biological sciences. Psychology Hypothalamus - drug effects Hypothalamus - physiology Intracellular Signaling Peptides and Proteins - pharmacology Male Medical sciences Metabolic diseases Motor Activity - drug effects Motor Activity - physiology Neurology Neuropeptides - pharmacology Obesity Obesity - physiopathology Orexin Receptor Antagonists Orexins Rats Rats, Sprague-Dawley Sleep - drug effects Substantia Nigra - drug effects Substantia Nigra - physiology Urea - analogs & derivatives Urea - pharmacology Vertebrates: nervous system and sense organs Wakefulness - drug effects |
| title | Mechanisms underlying obesity resistance associated with high spontaneous physical activity |
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