Bacterial Growth and Adaptation in Microdroplet Chemostats

Getting your bugs in a row: A microfluidic device for manipulating and monitoring the continuous growth of populations of bacteria within microdroplets was developed (see scheme). This device allows for monitoring hundreds of populations of bacteria to study changes in growth rates and the effects o...

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Veröffentlicht in:Angewandte Chemie International Edition 2013-08, Vol.52 (34), p.8908-8911
Hauptverfasser: Jakiela, Slawomir, Kaminski, Tomasz S., Cybulski, Olgierd, Weibel, Douglas B., Garstecki, Piotr
Format: Artikel
Sprache:eng
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Zusammenfassung:Getting your bugs in a row: A microfluidic device for manipulating and monitoring the continuous growth of populations of bacteria within microdroplets was developed (see scheme). This device allows for monitoring hundreds of populations of bacteria to study changes in growth rates and the effects of antibiotics, including the evolution of antibiotic resistance in real time.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201301524