Assessment of Platelet Indices in Patients with Neurodegenerative Diseases: Mean Platelet Volume Was Increased in Patients with Parkinson's Disease

Assessment of Platelet Indices in Patients with Neurodegenerative Diseases: Mean Platelet Volume Was Increased in Patients with Parkinson's Disease

Platelets induce chronic inflammation which is a key step in atherosclerosis and may be involved in the progression of neurodegenerative diseases (NDD). We aimed to measure the mean platelet volume (MPV) and platelet count (PLC) in NDD patients. The present study was designed to investigate the plat...

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Veröffentlicht in:Current Gerontology and Geriatrics Research 2013, Vol.2013 (2013), p.126-130
Hauptverfasser: Koçer, Abdulkadir, Yaman, Aslı, Niftaliyev, Elvin, Dürüyen, Hümeyra, Eryılmaz, Mehmet, Koçer, Emel
Format: Artikel
Sprache:eng
Schlagworte:
Alzheimer's disease
Analysis
Antidepressants
Atherosclerosis
Blood diseases
Blood platelets
Blood pressure
Diabetes
Heart attacks
Homocysteine
Hypertension
Inflammation
Laboratories
Measurement
Parkinson's disease
Pathogenesis
Risk factors
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Zusammenfassung:Platelets induce chronic inflammation which is a key step in atherosclerosis and may be involved in the progression of neurodegenerative diseases (NDD). We aimed to measure the mean platelet volume (MPV) and platelet count (PLC) in NDD patients. The present study was designed to investigate the platelet function by measuring MPV and PLC in NDD. A total of 182 outpatients with Alzheimer’s (AD) or Parkinson’s diseases (PD) were included. The control group consisted of 104 healthy subjects. Platelet count was similar between groups. MPV values of PD patients were higher than those of AD patients and controls (P
ISSN:1687-7063
1687-7071
DOI:10.1155/2013/986254