Algorithms of Ancestral Gene Length Reconstruction

Ancestral sequence reconstruction is a well-known problem in molecular evolution. The problem presented in this study is inspired by sequence reconstruction, but instead of leaf-associated sequences we consider only their lengths. We call this problem ancestral gene length reconstruction. It is a pr...

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Veröffentlicht in:BioMed research international 2013-01, Vol.2013 (2013), p.1-10
Hauptverfasser: Bolshoy, A., Kirzhner, Valery M.
Format: Artikel
Sprache:eng
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Zusammenfassung:Ancestral sequence reconstruction is a well-known problem in molecular evolution. The problem presented in this study is inspired by sequence reconstruction, but instead of leaf-associated sequences we consider only their lengths. We call this problem ancestral gene length reconstruction. It is a problem of finding an optimal labeling which minimizes the total length’s sum of the edges, where both a tree and nonnegative integers associated with corresponding leaves of the tree are the input. In this paper we give a linear algorithm to solve the problem on binary trees for the Manhattan cost function s(v,w)=|π(v)−π(w)|.
ISSN:2314-6133
2314-6141
DOI:10.1155/2013/472163