Modeling human liver biology using stem cell-derived hepatocytes

Stem cell-derived hepatocytes represent promising models to study human liver biology and disease. This concise review discusses the recent progresses in the field, with a focus on human liver disease, drug metabolism and virus infection.

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Bibliographische Detailangaben
Veröffentlicht in:	International journal of molecular sciences 2013-11, Vol.14 (11), p.22011-22021
Hauptverfasser:	Sun, Pingnan, Zhou, Xiaoling, Farnworth, Sarah L, Patel, Arvind H, Hay, David C
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Differentiation Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Hepatocytes - metabolism Hepatocytes - pathology Humans Liver - cytology Liver - metabolism Liver - physiopathology Liver Diseases - drug therapy Liver Diseases - metabolism Liver Diseases - physiopathology Liver Diseases - virology Review
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Beschreibung
Zusammenfassung:	Stem cell-derived hepatocytes represent promising models to study human liver biology and disease. This concise review discusses the recent progresses in the field, with a focus on human liver disease, drug metabolism and virus infection.
ISSN:	1422-0067 1661-6596 1422-0067
DOI:	10.3390/ijms141122011