Building synthetic cellular organization

Building synthetic cellular organization

The elaborate spatial organization of cells enhances, restricts, and regulates protein-protein interactions. However, the biological significance of this organization has been difficult to study without ways of directly perturbing it. We highlight synthetic biology tools for engineering novel cellul...

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Veröffentlicht in:Molecular biology of the cell 2013-12, Vol.24 (23), p.3585-3587
Hauptverfasser: Polka, Jessica K, Silver, Pamela A
Format: Artikel
Sprache:eng
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Artificial Cells - metabolism
Models, Biological
Subcellular Fractions - metabolism
Synthetic Biology - methods
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container_title Molecular biology of the cell
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creator Polka, Jessica K
Silver, Pamela A
description The elaborate spatial organization of cells enhances, restricts, and regulates protein-protein interactions. However, the biological significance of this organization has been difficult to study without ways of directly perturbing it. We highlight synthetic biology tools for engineering novel cellular organization, describing how they have been, and can be, used to advance cell biology.
doi_str_mv 10.1091/mbc.E13-03-0155
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subjects Artificial Cells - metabolism
Models, Biological
Subcellular Fractions - metabolism
Synthetic Biology - methods
title Building synthetic cellular organization
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