Cooperative, Nanoparticle-Enabled Thermal Therapy of Breast Cancer

Cooperative, Nanoparticle-Enabled Thermal Therapy of Breast Cancer

Hollow gold nanoshells are more efficient in heat generation triggered by near infrared laser when they are loaded into porous silicon particles, which results in effective cancer‐cell killing in vitro and in vivo. Collective electromagnetic coupling of nanoconfined hollow gold nanoshells leads to d...

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Veröffentlicht in:Advanced healthcare materials 2012-01, Vol.1 (1), p.84-89
Hauptverfasser: Shen, Haifa, You, Jian, Zhang, Guodong, Ziemys, Arturas, Li, Qingpo, Bai, Litao, Deng, Xiaoyong, Erm, Donald R., Liu, Xuewu, Li, Chun, Ferrari, Mauro
Format: Artikel
Sprache:eng
Schlagworte:
Ablation
Animals
Breast cancer
Cancer
Cell Line, Tumor
Gold
Health care
Heat generation
hollow nanoshells
Hyperthermia, Induced - methods
Killing
Mice
nanoassembly
Nanoparticles - chemistry
Nanoparticles - therapeutic use
Nanoparticles - ultrastructure
Nanostructure
Neoplasms, Experimental - pathology
Neoplasms, Experimental - therapy
Particle Size
Porous silicon
thermal therapy
Treatment Outcome
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Zusammenfassung:Hollow gold nanoshells are more efficient in heat generation triggered by near infrared laser when they are loaded into porous silicon particles, which results in effective cancer‐cell killing in vitro and in vivo. Collective electromagnetic coupling of nanoconfined hollow gold nanoshells leads to dramatic enhancement of thermal ablation.
ISSN:2192-2640
2192-2659
DOI:10.1002/adhm.201100005