Long-term functional health status and exercise test variables for patients with pulmonary atresia with intact ventricular septum: A Congenital Heart Surgeons Society study

Long-term functional health status and exercise test variables for patients with pulmonary atresia with intact ventricular septum: A Congenital Heart Surgeons Society study

Background A bias favoring biventricular (BV) repair exists regarding choice of repair pathway for patients with pulmonary atresia with intact ventricular septum (PAIVS). We sought to determine the implications of moving borderline candidates down a BV route in terms of late functional health status...

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Veröffentlicht in:The Journal of thoracic and cardiovascular surgery 2013-04, Vol.145 (4), p.1018-1027.e3
Hauptverfasser: Karamlou, Tara, MD, MSc, Poynter, Jeffrey A., MD, Walters, Henry L., MD, Rhodes, Jonathan, MD, Bondarenko, Igor, MD, Pasquali, Sara K., MD, Fuller, Stephanie M., MD, Lambert, Linda M., RN, Blackstone, Eugene H., MD, Jacobs, Marshall L., MD, Duncan, Kim, MD, Caldarone, Christopher A., MD, Williams, William G., MD, McCrindle, Brian W., MD, MPH
Format: Artikel
Sprache:eng
Schlagworte:
Cardiothoracic Surgery
Child
Child, Preschool
Exercise Test
Female
Health Status
Heart Defects, Congenital - physiopathology
Heart Defects, Congenital - surgery
Humans
Infant
Infant, Newborn
Male
Pulmonary Atresia - physiopathology
Pulmonary Atresia - surgery
Time Factors
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Zusammenfassung:Background A bias favoring biventricular (BV) repair exists regarding choice of repair pathway for patients with pulmonary atresia with intact ventricular septum (PAIVS). We sought to determine the implications of moving borderline candidates down a BV route in terms of late functional health status (FHS) and exercise capacity (EC). Methods Between 1987 and 1997, 448 neonates with PAIVS were enrolled in a multi-institutional study. Late EC and FHS were assessed following repair (mean 14 years) using standardized exercise testing and 3 validated FHS instruments. Relationships between FHS, EC, morphology, and 3 end states (ie, BV, univentricular [UV], or 1.5-ventricle repair [1.5V]) were evaluated. Results One hundred two of 271 end state survivors participated (63 BV, 25 UV, and 14 1.5V). Participants had lower FHS scores in domains of physical functioning ( P  
ISSN:0022-5223
1097-685X
DOI:10.1016/j.jtcvs.2012.11.092